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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68350
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a1
Name: nuclear receptor subfamily 5, group A, member 1
Acc ID: CHEBI:16243
Term: quercetin
Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.
Chemical ID: MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a1increases expressionEXP 6480464CTDQuercetin results in increased expression of NR5A1 mRNAPMID:27111109
Nr5a1multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Fenitrothion results in decreased expression of NR5A1 mRNA]; Quercetin inhibits the reaction [Zinc Oxide analog results in decreased expression of NR5A1 mRNA]PMID:26264430 PMID:27111109
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