GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | decreases expression | EXP | | 6480464 | CTD | Quercetin results in decreased expression of CCL2 mRNA; Quercetin results in decreased expression of CCL2 protein | PMID:10925121 PMID:11053056 | Ccl2 | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA] | PMID:10541287 | Ccl2 | decreases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Quercetin results in decreased expression of CCL2 mRNA; Quercetin results in decreased expression of CCL2 protein | PMID:16794257 PMID:24465016 | Ccl2 | decreases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of CCL2 mRNA | PMID:21756928 PMID:21967610 | Ccl2 | decreases secretion | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased secretion of CCL2 protein | PMID:17191019 PMID:20816778 PMID:21967610 | Ccl2 | increases expression | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of CCL2 mRNA | PMID:21371465 | Ccl2 | increases secretion | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | Quercetin results in increased secretion of CCL2 protein | PMID:21371465 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | dorsomorphin inhibits the reaction [Quercetin results in decreased expression of CCL2 mRNA]; Quercetin affects the reaction [CCL2 protein affects the activity of PTGS2 protein]; Quercetin inhibits the reaction [Calcium Chloride results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [CCL2 protein affects the abundance of A2-E (N-retinylidene-N-retinylethanolamine)]; Quercetin inhibits the reaction [CCL2 protein affects the expression of BAX mRNA]; Quercetin inhibits the reaction [Dietary Fats results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Dietary Fats results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Palmitic Acid results in increased expression of CCL2 protein]; Quercetin inhibits the reaction [Vitamin E deficiency results in increased expression of CCL2 protein] | PMID:19735175 PMID:20361964 PMID:22210036 PMID:22728078 PMID:22869926 PMID:24465016 PMID:25614714 | Ccl2 | multiple interactions | ISO | CCL2 (Homo sapiens) | 6480464 | CTD | [Quercetin co-treated with dinitrophenyl-human serum albumin conjugate] affects the secretion of CCL2 protein; Quercetin analog inhibits the reaction [24-hydroxycholesterol results in increased expression of CCL2 mRNA]; Quercetin analog inhibits the reaction [27-hydroxycholesterol results in increased expression of CCL2 mRNA]; Quercetin analog inhibits the reaction [[24-hydroxycholesterol co-treated with 27-hydroxycholesterol co-treated with cholest-5-en-3 beta,7 alpha-diol] results in increased expression of CCL2 mRNA]; Quercetin analog inhibits the reaction [cholest-5-en-3 beta,7 alpha-diol results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with TNF protein] results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of MCP1 mRNA]; Quercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [PD168393 results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [S100B protein results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [TNF protein results in increased expression of CCL2 protein] | PMID:16794257 PMID:17103373 PMID:17880982 PMID:18489909 PMID:20438634 PMID:20542118 PMID:21371465 PMID:21756928 PMID:21967610 PMID:24802026 PMID:31672514 PMID:9292787 | | ||||||||||||||||||||||
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