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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3639 Species: Rattus norvegicus RGD Object: Gene Symbol: Scnn1a Name: sodium channel, nonvoltage-gated 1 alpha

Acc ID: CHEBI:16243 Term: quercetin Definition: A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. CasRN: 117-39-5 Chemical ID: MESH:D011794

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Quercetin inhibits the reaction [Sodium Chloride results in increased expression of SCNN1A mRNA]	PMID:14985096
increases expression	ISO	RGD:736324	6480464	CTD	Quercetin results in increased expression of SCNN1A mRNA	PMID:21632981