GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ar | increases expression | EXP | | 6480464 | CTD | Quercetin results in increased expression of AR mRNA | PMID:23200735 | Ar | multiple interactions | EXP | | 6480464 | CTD | [Quercetin co-treated with Bucladesine] results in increased expression of AR mRNA; Quercetin inhibits the reaction [Atrazine results in increased expression of AR mRNA]; Quercetin promotes the reaction [Atrazine results in increased expression of AR mRNA] | PMID:22372587 PMID:23200735 | Ar | decreases activity | ISO | AR (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased activity of AR protein | PMID:16239064 | Ar | decreases expression | ISO | AR (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of AR mRNA; Quercetin results in decreased expression of AR protein | PMID:11238180 PMID:12391264 PMID:15661808 PMID:16239064 PMID:24726691 | Ar | increases activity | ISO | AR (Homo sapiens) | 6480464 | CTD | Quercetin results in increased activity of AR protein mutant form | PMID:12391264 | Ar | increases expression | ISO | AR (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of AR mRNA; Quercetin results in increased expression of AR protein | PMID:12391264 PMID:27132804 | Ar | multiple interactions | ISO | AR (Homo sapiens) | 6480464 | CTD | [[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR mRNA; [[Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter] which results in increased expression of AR protein; [Quercetin co-treated with arctigenin] results in decreased expression of AR protein; [Quercetin co-treated with Curcumin] results in decreased methylation of AR promoter; [Quercetin co-treated with mibolerone] promotes the reaction [AR protein binds to JUN protein]; [Quercetin co-treated with mibolerone] promotes the reaction [SP1 protein binds to JUN protein binds to AR protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of BAX protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CASP3 protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1A protein]; AR protein affects the reaction [[Curcumin co-treated with Quercetin] results in increased expression of CDKN1B protein]; Curcumin promotes the reaction [Quercetin results in increased expression of AR mRNA]; Curcumin promotes the reaction [Quercetin results in increased expression of AR protein]; pyrazolanthrone affects the reaction [Quercetin inhibits the reaction [mibolerone results in increased expression of AR protein]]; Quercetin affects the reaction [mibolerone affects the localization of AR protein]; Quercetin inhibits the reaction [AR protein results in increased expression of KLK3 mRNA]; Quercetin inhibits the reaction [mibolerone results in increased expression of AR protein]; Quercetin inhibits the reaction [mibolerone results in increased phosphorylation of AR protein]; Quercetin inhibits the reaction [SP1 protein promotes the reaction [AR protein results in increased expression of HK2 mRNA]]; Quercetin inhibits the reaction [SP1 protein promotes the reaction [AR protein results in increased expression of KLK3 mRNA]]; Quercetin inhibits the reaction [SP1 protein results in increased expression of AR mRNA]; Quercetin promotes the reaction [AR protein binds to SP1 protein]; Quercetin promotes the reaction [Curcumin results in increased expression of AR mRNA]; Quercetin promotes the reaction [Curcumin results in increased expression of AR protein]; Quercetin promotes the reaction [mibolerone promotes the reaction [SP1 protein binds to AR protein]]; Quercetin results in increased activity of and results in increased localization of AR protein | PMID:11238180 PMID:12391264 PMID:15661808 PMID:20148354 PMID:25380086 PMID:27132804 | | ||||||||||||||||||||||
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