GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
1550709
Species:
Mus musculus
RGD Object:
Gene
Symbol:
Cxcl10
Name:
chemokine (C-X-C motif) ligand 10
Acc ID:
CHEBI:16243
Term:
quercetin
Definition:
A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions.
CasRN:
117-39-5
Chemical ID:
MESH:D011794
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions EXP 6480464 CTD Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Quercetin inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA] PMID:19426678 multiple interactions ISO RGD:1352024 6480464 CTD Quercetin inhibits the reaction [S100B protein results in increased expression of CXCL10 mRNA] PMID:17103373 multiple interactions EXP 6480464 CTD Quercetin inhibits the reaction [TNF protein promotes the reaction [CREBBP protein binds to CXCL10 promoter]] Quercetin inhibits the reaction [TNF protein results in increased expression of CXCL10 mRNA] Quercetin inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CXCL10 promoter]] PMID:17449583 decreases expression ISO RGD:1352024 6480464 CTD Quercetin results in decreased expression of CXCL10 mRNA PMID:21756928 decreases secretion ISO RGD:1352024 6480464 CTD Quercetin results in decreased secretion of CXCL10 protein PMID:21756928 multiple interactions ISO RGD:1352024 6480464 CTD Quercetin inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased secretion of CXCL10 protein] PMID:21756928 decreases expression ISO RGD:1352024 6480464 CTD Quercetin results in decreased expression of CXCL10 mRNA PMID:21756928 PMID:21967610 decreases secretion ISO RGD:1352024 6480464 CTD Quercetin results in decreased secretion of CXCL10 protein PMID:21756928 PMID:21967610 multiple interactions ISO RGD:1352024 6480464 CTD Quercetin inhibits the reaction [PD168393 results in increased expression of CXCL10 mRNA] Quercetin promotes the reaction [leptomycin B results in decreased secretion of CXCL10 protein] PMID:21967610