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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1decreases expressionISOCCND1 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased expression of CCND1 proteinPMID:26482937
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of CCND1 mRNAPMID:27049278 PMID:32949572
Ccnd1multiple interactionsISOCCND1 (Homo sapiens)6480464CTDnaringin inhibits the reaction [Hydrogen Peroxide results in decreased expression of CCND1 protein]; resveratrol inhibits the reaction [Hydrogen Peroxide results in increased expression of CCND1 mRNA]PMID:26482937 PMID:27049278
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