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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3733
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod3
Name: superoxide dismutase 3
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod3multiple interactionsISOSod3 (Mus musculus)6480464CTDSOD3 protein inhibits the reaction [[Copper co-treated with Hydrogen Peroxide] results in increased degradation of Hyaluronic Acid]PMID:18165226
Sod3multiple interactionsISOSOD3 (Homo sapiens)6480464CTDSOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]]; SOD3 promotes the reaction [GW 4064 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein]]PMID:25496033
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