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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3624
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atxn1
Name: ataxin 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atxn1affects localizationISOATXN1 (Homo sapiens)6480464CTDHydrogen Peroxide affects the localization of ATXN1 protein mutant formPMID:12893416
Atxn1increases expressionISOATXN1 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of ATXN1 mRNAPMID:18951874
Atxn1multiple interactionsISOATXN1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of ATXN1 protein mutant form]; Buthionine Sulfoximine promotes the reaction [Hydrogen Peroxide affects the localization of ATXN1 protein mutant form]PMID:12893416
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