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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3317
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgr
Name: progesterone receptor
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgrincreases expressionISOPgr (Mus musculus)6480464CTDHydrogen Peroxide results in increased expression of PGR mRNAPMID:21220312
Pgrmultiple interactionsISOPgr (Mus musculus)6480464CTDN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Hydrogen Peroxide results in increased expression of PGR mRNA]; U 0126 inhibits the reaction [Hydrogen Peroxide results in increased expression of PGR mRNA]PMID:21220312
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