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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Insr
Name: insulin receptor
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Insrincreases phosphorylationISOINSR (Homo sapiens)6480464CTDHydrogen Peroxide results in increased phosphorylation of INSR proteinPMID:22482891
Insrmultiple interactionsISOINSR (Homo sapiens)6480464CTDFANCA protein affects the reaction [Hydrogen Peroxide results in increased phosphorylation of INSR protein]; FANCC protein affects the reaction [Hydrogen Peroxide results in increased phosphorylation of INSR protein]PMID:22482891
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