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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2803
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgcr
Name: 3-hydroxy-3-methylglutaryl-CoA reductase
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgcrincreases expressionISOHMGCR (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of HMGCR mRNAPMID:12414654
Hmgcrmultiple interactionsISOHMGCR (Homo sapiens)6480464CTD[isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of HMGCR mRNAPMID:18032389
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