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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atf1
Name: activating transcription factor 1
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atf1decreases expressionISOATF1 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased expression of ATF1 mRNAPMID:18951874
Atf1increases phosphorylationISOATF1 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased phosphorylation of ATF1 proteinPMID:20302854
Atf1multiple interactionsISOATF1 (Homo sapiens)6480464CTDMycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of ATF1 protein]PMID:20302854
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