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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68384
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1increases expressionEXP 6480464CTDEthanol results in increased expression of CCND1 proteinPMID:18506933
Ccnd1multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Ethanol results in increased expression of CCND1 protein]PMID:18506933
Ccnd1affects expressionISOCcnd1 (Mus musculus)6480464CTDEthanol affects the expression of CCND1 mRNAPMID:30319688
Ccnd1affects splicingISOCcnd1 (Mus musculus)6480464CTDEthanol affects the splicing of CCND1 mRNAPMID:30319688
Ccnd1decreases expressionISOCcnd1 (Mus musculus)6480464CTDEthanol results in decreased expression of CCND1 mRNAPMID:34492310
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDEthanol results in increased expression of CCND1 mRNAPMID:12720008
Ccnd1increases expressionISOCcnd1 (Mus musculus)6480464CTDEthanol results in increased expression of CCND1 mRNAPMID:25460735 PMID:30319688
Ccnd1multiple interactionsISOCcnd1 (Mus musculus)6480464CTDNR1H4 gene mutant form inhibits the reaction [Ethanol results in increased expression of CCND1 mRNA]PMID:25460735
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