Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg2increases expressionEXP 6480464CTDEthanol results in increased expression of ABCG2 mRNAPMID:34217791 PMID:35608386
Abcg2multiple interactionsEXP 6480464CTD[Aflatoxin B1 co-treated with Ethanol] results in increased expression of ABCG2 mRNA; Sildenafil Citrate inhibits the reaction [[Aflatoxin B1 co-treated with Ethanol] results in increased expression of ABCG2 mRNA]; Tadalafil inhibits the reaction [[Aflatoxin B1 co-treated with Ethanol] results in increased expression of ABCG2 mRNA]PMID:35608386
Abcg2decreases expressionISOAbcg2 (Mus musculus)6480464CTDEthanol results in decreased expression of ABCG2 mRNAPMID:19167417
Abcg2increases expressionISOABCG2 (Homo sapiens)6480464CTDEthanol results in increased expression of ABCG2 mRNA; Ethanol results in increased expression of ABCG2 proteinPMID:34217791
Abcg2multiple interactionsISOABCG2 (Homo sapiens)6480464CTD[2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Ethanol co-treated with Benzo(a)pyrene]] which results in increased expression of ABCG2 mRNA; [Ethanol co-treated with Benzo(a)pyrene] results in increased expression of ABCG2 mRNA; GW 4064 inhibits the reaction [Ethanol results in increased expression of ABCG2 mRNA]PMID:34217791 PMID:35412187
Go Back to source page   Continue to Ontology report