Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620588
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd14
Name: CD14 molecule
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd14increases expressionEXP 6480464CTDEthanol results in increased expression of CD14 mRNA; Ethanol results in increased expression of CD14 proteinPMID:20861358 PMID:28852734 PMID:36453646
Cd14multiple interactionsEXP 6480464CTDCannabinoids inhibits the reaction [Ethanol results in increased expression of CD14 mRNA]; platycodin D inhibits the reaction [Ethanol results in increased expression of CD14 protein]PMID:28852734 PMID:36453646
Cd14decreases response to substanceISOCd14 (Mus musculus)6480464CTDCD14 gene mutant form results in decreased susceptibility to EthanolPMID:21309947
Cd14increases expressionISOCd14 (Mus musculus)6480464CTDEthanol results in increased expression of CD14 mRNAPMID:19167417
Cd14multiple interactionsISOCd14 (Mus musculus)6480464CTD[CD14 protein results in increased susceptibility to Lipopolysaccharides] which affects the susceptibility to EthanolPMID:21266194
Go Back to source page   Continue to Ontology report