GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | increases expression | EXP | | 6480464 | CTD | Ethanol results in increased expression of SOD2 mRNA; Ethanol results in increased expression of SOD2 protein | PMID:10787391 PMID:24769256 | Sod2 | multiple interactions | EXP | | 6480464 | CTD | salvianolic acid B inhibits the reaction [Ethanol results in increased expression of SOD2 protein]; Vitamin E affects the reaction [Ethanol affects the activity of SOD2 protein] | PMID:10787391 PMID:24769256 | Sod2 | decreases activity | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Ethanol results in decreased activity of SOD2 protein | PMID:20016022 | Sod2 | decreases expression | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Ethanol results in decreased expression of SOD2 mRNA; Ethanol results in decreased expression of SOD2 protein | PMID:24065054 PMID:24144995 | Sod2 | increases activity | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Ethanol results in increased activity of SOD2 protein | PMID:19063909 PMID:20016022 | Sod2 | increases expression | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Ethanol results in increased expression of SOD2 mRNA; Ethanol results in increased expression of SOD2 protein | PMID:19951287 PMID:24095927 PMID:25460735 | Sod2 | multiple interactions | ISO | Sod2 (Mus musculus) | 6480464 | CTD | Deferoxamine inhibits the reaction [SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]]; NR1H4 gene mutant form inhibits the reaction [Ethanol results in increased expression of SOD2 mRNA]; SOD2 protein affects the reaction [Ethanol results in decreased expression of TFAM protein]; SOD2 protein affects the reaction [Ethanol results in increased abundance of Iron]; SOD2 protein affects the reaction [Ethanol results in increased expression of NOS2 protein]; SOD2 protein inhibits the reaction [Ethanol results in increased expression of NOS2 protein] | PMID:19063909 PMID:20016022 PMID:25460735 | |
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