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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3194
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nppb
Name: natriuretic peptide B
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nppbdecreases expressionEXP 6480464CTDEthanol results in decreased expression of NPPB proteinPMID:25598224
Nppbmultiple interactionsEXP 6480464CTD3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]PMID:35066094
Nppbdecreases expressionISONPPB (Homo sapiens)6480464CTDEthanol results in decreased expression of NPPB mRNAPMID:31059573
Nppbmultiple interactionsISONppb (Mus musculus)6480464CTDEthanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]PMID:35066094
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