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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2993
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lcat
Name: lecithin cholesterol acyltransferase
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lcatdecreases activityEXP 6480464CTDEthanol results in decreased activity of LCAT proteinPMID:28442378
Lcatmultiple interactionsEXP 6480464CTDzingerone inhibits the reaction [Ethanol results in decreased activity of LCAT protein]PMID:28442378
Lcatincreases expressionISOLcat (Mus musculus)6480464CTDEthanol results in increased expression of LCAT mRNAPMID:30319688
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