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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2254
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Calca
Name: calcitonin-related polypeptide alpha
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Calcaaffects response to substanceEXP 6480464CTDCALCA protein affects the susceptibility to EthanolPMID:15046732
Calcadecreases expressionEXP 6480464CTDEthanol results in decreased expression of CALCA proteinPMID:23376407
Calcamultiple interactionsEXP 6480464CTD[Ethanol co-treated with lead acetate] results in increased expression of CALCA proteinPMID:23376407
Calcaincreases expressionISOCalca (Mus musculus)6480464CTDEthanol results in increased expression of CALCA mRNAPMID:34755883
Calcamultiple interactionsISOCalca (Mus musculus)6480464CTD[Capsaicin co-treated with Ethanol] results in increased expression of CALCA protein; [Sodium Chloride co-treated with Ethanol] results in increased expression of CALCA protein; CALCA protein affects the reaction [Capsaicin results in decreased susceptibility to Ethanol]PMID:18054007
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