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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202 Species: Rattus norvegicus RGD Object: Gene Symbol: Bdnf Name: brain-derived neurotrophic factor

Acc ID: CHEBI:16236 Term: ethanol Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group. CasRN: 64-17-5 Chemical ID: MESH:D000431

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	Ethanol results in increased expression of BDNF mRNA	PMID:18713641
decreases expression	EXP		6480464	CTD	Ethanol results in decreased expression of BDNF protein	PMID:19100286