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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2049
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Adora2a
Name: adenosine A2a receptor
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Adora2amultiple interactionsEXP 6480464CTDADORA2A protein affects the reaction [[moxonidine binds to and results in increased activity of NISCH protein] which results in decreased susceptibility to Ethanol]PMID:22613216
Adora2adecreases expressionISOAdora2a (Mus musculus)6480464CTDEthanol results in decreased expression of ADORA2A mRNAPMID:21955143
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