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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614993 Species: Mus musculus RGD Object: Gene Symbol: Aldh1l1 Name: aldehyde dehydrogenase 1 family, member L1

Acc ID: CHEBI:16236 Term: ethanol Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group. CasRN: 64-17-5 Chemical ID: MESH:D000431

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases activity	ISO	RGD:621294	6480464	CTD	Ethanol results in decreased activity of ALDH1L1 protein	PMID:16385189
decreases expression	ISO	RGD:621294	6480464	CTD	Ethanol results in decreased expression of ALDH1L1 mRNA	PMID:17920746
multiple interactions	ISO	RGD:621294	6480464	CTD	Folic Acid affects the reaction [Ethanol results in decreased activity of ALDH1L1 protein]	PMID:16385189