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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3684
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc11a2
Name: solute carrier family 11 member 2
Acc ID: CHEBI:16170
Term: mercury(0)
Definition: Elemental mercury of oxidation state zero.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc11a2decreases expressionISOSLC11A2 (Homo sapiens)6480464CTDMercury results in decreased expression of SLC11A2 mRNAPMID:25772431
Slc11a2increases uptakeISOSLC11A2 (Homo sapiens)6480464CTDSLC11A2 mRNA results in increased uptake of MercuryPMID:25772431
Slc11a2increases uptakeISOSlc11a2 (Mus musculus)6480464CTDSLC11A2 results in increased uptake of MercuryPMID:25772431
Slc11a2multiple interactionsISOSLC11A2 (Homo sapiens)6480464CTD[HAMP protein results in decreased expression of SLC11A2 mRNA] which results in decreased uptake of MercuryPMID:25772431
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