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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2202
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bdnf
Name: brain-derived neurotrophic factor
Acc ID: CHEBI:16170
Term: mercury(0)
Definition: Elemental mercury of oxidation state zero.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bdnfaffects response to substanceISOBDNF (Homo sapiens)6480464CTDBDNF polymorphism affects the susceptibility to MercuryPMID:16301096
Bdnfdecreases expressionISOBDNF (Homo sapiens)6480464CTDMercury results in decreased expression of BDNF mRNAPMID:19937285
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