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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3615
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S100b
Name: S100 calcium binding protein B
Acc ID: CHEBI:16134
Term: ammonia
Definition: An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
Chemical ID: MESH:D000641
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S100bincreases secretionEXP 6480464CTDAmmonia results in increased secretion of S100B proteinPMID:23284918 PMID:23880158
S100bmultiple interactionsEXP 6480464CTD2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Ammonia results in increased secretion of S100B protein]; [Furosemide results in decreased activity of SLC12A2 protein] affects the reaction [Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]]; [Furosemide results in decreased activity of SLC12A2 protein] inhibits the reaction [Ammonia results in increased secretion of S100B protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Ammonia results in increased secretion of S100B protein]; resveratrol inhibits the reaction [Ammonia results in increased secretion of S100B protein]; Thioctic Acid inhibits the reaction [Ammonia results in increased secretion of S100B protein]PMID:23284918 PMID:23880158
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