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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2892 Species: Rattus norvegicus RGD Object: Gene Symbol: Il1r1 Name: interleukin 1 receptor, type I

Acc ID: CHEBI:16130 Term: DDT Definition: A chlorophenylethane that has formula C14H9Cl5. CasRN: 50-29-3 Chemical ID: MESH:D003634

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	DDT results in increased expression of IL1R1 mRNA	PMID:11948501
decreases expression	EXP		6480464	CTD	DDT results in decreased expression of IL1R1 mRNA	PMID:11948501