Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	70500
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Mapk1
Name:	mitogen activated protein kinase 1

Acc ID:	CHEBI:16118
Term:	berberine
Definition:	A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID:	MESH:D001599

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Mapk1	decreases phosphorylation	EXP		6480464	CTD	Berberine results in decreased phosphorylation of MAPK1 protein	PMID:18294404

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.