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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3932
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ucp2
Name: uncoupling protein 2
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp2increases expressionISOUcp2 (Mus musculus)6480464CTDBerberine results in increased expression of UCP2 mRNAPMID:37511356
Ucp2multiple interactionsISOUcp2 (Mus musculus)6480464CTDBerberine inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA]PMID:28533128
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