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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2810
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hnf4a
Name: hepatocyte nuclear factor 4, alpha
Acc ID: CHEBI:16118
Term: berberine
Definition: A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID: MESH:D001599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hnf4amultiple interactionsEXP 6480464CTDBerberine inhibits the reaction [Fructose results in decreased expression of HNF4A mRNA]; Berberine inhibits the reaction [Fructose results in decreased expression of HNF4A protein]PMID:18563319
Hnf4amultiple interactionsISOHnf4a (Mus musculus)6480464CTDBerberine inhibits the reaction [Ethanol results in decreased expression of HNF4 protein]PMID:25455889
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