Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2375
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Col2a1
Name:	collagen type II alpha 1 chain

Acc ID:	CHEBI:16118
Term:	berberine
Definition:	A botanical anti-fungal agent that has formula C20H18NO4.
Chemical ID:	MESH:D001599

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Col2a1	decreases expression	ISO	COL2A1 (Homo sapiens)	6480464	CTD	Berberine results in decreased expression of COL2A1 mRNA	PMID:26478571

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.