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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1310664 Species: Rattus norvegicus RGD Object: Gene Symbol: Tpr Name: translocated promoter region, nuclear basket protein

Acc ID: CHEBI:15956 Term: biotin Definition: An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. CasRN: 58-85-5 Chemical ID: MESH:D001710

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:1321699	6480464	CTD	Biotin results in increased expression of TPR mRNA	PMID:15219929