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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2129 Species: Rattus norvegicus RGD Object: Gene Symbol: Apob Name: apolipoprotein B

Acc ID: CHEBI:15940 Term: nicotinic acid Definition: A pyridinemonocarboxylic acid in which the carboxy group is located at position 3. CasRN: 59-67-6 Chemical ID: MESH:D009525

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735787	6480464	CTD	[Niacin co-treated with Lovastatin] results in decreased expression of APOB protein	PMID:12633795
multiple interactions	ISO	RGD:735787	6480464	CTD	[Niacin co-treated with Simvastatin] results in decreased expression of APOB protein	PMID:18471454
decreases expression	ISO	RGD:735787	6480464	CTD	Niacin results in decreased expression of APOB protein	PMID:11701466 PMID:15539964
decreases expression	ISO	RGD:735787	6480464	CTD	Niacin results in decreased expression of APOB protein	PMID:15539964 PMID:11701466