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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733803 Species: Homo sapiens RGD Object: Gene Symbol: GADD45A Name: growth arrest and DNA-damage-inducible, alpha

Acc ID: CHEBI:15930 Term: atrazine Definition: A chloro-1,3,5-triazine herbicide that has formula C8H14ClN5. CasRN: 1912-24-9 Chemical ID: MESH:D001280

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Atrazine promotes the reaction [arsenic trioxide results in increased expression of GADD45A mRNA]	PMID:11678611
multiple interactions	ISO	RGD:736689	6480464	CTD	[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GADD45A mRNA	PMID:22515965