GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr1 | increases expression | EXP | | 6480464 | CTD | Atrazine results in increased expression of ESR1 protein | PMID:33766575 | Esr1 | affects binding | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | Atrazine binds to ESR1 protein | PMID:14579009 PMID:8858116 | Esr1 | decreases expression | ISO | Esr1 (Rattus norvegicus) | 6480464 | CTD | Atrazine results in decreased expression of ESR1 mRNA | PMID:22285353 | Esr1 | increases expression | ISO | Esr1 (Rattus norvegicus) | 6480464 | CTD | Atrazine results in increased expression of ESR1 mRNA; Atrazine results in increased expression of ESR1 protein | PMID:23200735 PMID:34600026 | Esr1 | multiple interactions | ISO | Esr1 (Rattus norvegicus) | 6480464 | CTD | Atrazine inhibits the reaction [Bucladesine results in increased expression of ESR1 mRNA]; Atrazine inhibits the reaction [Estradiol binds to ESR1 protein]; Quercetin promotes the reaction [Atrazine results in increased expression of ESR1 mRNA] | PMID:15056801 PMID:21693180 PMID:23200735 | Esr1 | multiple interactions | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | Atrazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]; Atrazine inhibits the reaction [Estradiol binds to ESR1 protein]; ESR1 protein promotes the reaction [Atrazine results in increased expression of CCN2 protein]; ESR1 protein promotes the reaction [Atrazine results in increased expression of FOS protein] | PMID:14579009 PMID:25616260 PMID:8858116 | |
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