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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589755
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tyr
Name: tyrosinase
Acc ID: CHEBI:15846
Term: NAD(+)
Definition: The oxidised form of nicotinamide adenine dinucleotide found in all living cells. In metabolism, NAD(+) is involved in redox reactions, carrying electrons from one reaction to another.
Chemical ID: MESH:D009243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tyrincreases oxidationISOTYR (Homo sapiens)6480464CTD[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NADPMID:20685355
Tyrmultiple interactionsISOTYR (Homo sapiens)6480464CTDethylenediamine inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]; Glutathione inhibits the reaction [[TYR protein results in increased oxidation of caffeic acid phenethyl ester] which results in increased oxidation of NAD]PMID:20685355
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