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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2917
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Insr
Name: insulin receptor
Acc ID: CHEBI:15600
Term: (+)-catechin
Definition: The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.
Chemical ID: MESH:D002392
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Insrmultiple interactionsEXP 6480464CTDCatechin inhibits the reaction [Glucose results in decreased expression of and results in decreased phosphorylation of INSR protein]; Catechin results in increased expression of and results in increased phosphorylation of INSR proteinPMID:29981789
Insrmultiple interactionsISOINSR (Homo sapiens)6480464CTDCatechin inhibits the reaction [Glucose results in decreased expression of INSR protein modified form]; Catechin inhibits the reaction [Glucose results in decreased expression of INSR protein]PMID:24262486
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