Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
1,3-bis(4-hydroxyphenyl)-4-methyl-5-(4-(2-piperidinylethoxy)phenol)-1H-pyrazole inhibits the reaction [Estradiol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein]]; 2,3-bis(4-hydroxyphenyl)-propionitrile inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein]; 4,4',4''-(4-propyl-((1)H)-pyrazole-1,3,5-triyl) tris-phenol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein]; 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [Estradiol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein]]; [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of SOD2 mRNA; [Oxygen deficiency co-treated with Oxygen] inhibits the reaction [MAPK11 protein binds to SOD2 protein]; [Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein; [Oxygen deficiency co-treated with Oxygen] results in increased expression of SOD2 protein; Estradiol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] inhibits the reaction [MAPK11 protein binds to SOD2 protein]]; Estradiol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased activity of SOD2 protein]; Pertussis Toxin inhibits the reaction [Oxygen results in increased expression of SOD2 mRNA]; Pertussis Toxin inhibits the reaction [Oxygen results in increased expression of SOD2 protein]
Oxygen deficiency results in decreased expression of SOD2 mRNA; Oxygen deficiency results in decreased expression of SOD2 protein; Oxygen results in decreased expression of SOD2 mRNA; Oxygen results in decreased expression of SOD2 protein
Oxygen deficiency results in increased expression of SOD2 protein; Oxygen results in increased expression of SOD2 mRNA; Oxygen results in increased expression of SOD2 protein
[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased expression of SOD2 protein; [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SOD2 mRNA; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 protein]; Emodin inhibits the reaction [Oxygen deficiency results in decreased activity of SOD2 protein]; Emodin inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA]; gingerol inhibits the reaction [Oxygen deficiency results in decreased activity of SOD2 protein]; gingerol inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA]; IL6 protein inhibits the reaction [[[Oxygen deficiency co-treated with Glucose deficiency] co-treated with Oxygen] results in decreased expression of SOD2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxygen deficiency results in decreased activity of SOD2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA]; MIR34C promotes the reaction [Oxygen results in decreased expression of SOD2 mRNA]; MIR34C promotes the reaction [Oxygen results in decreased expression of SOD2 protein]; Oxygen affects the reaction [SOD2 gene mutant form affects the susceptibility to Paraquat]; Oxygen affects the reaction [SOD2 gene mutant form results in increased susceptibility to Oxygen]; SRT1720 inhibits the reaction [Oxygen results in decreased expression of SOD2 mRNA]; SRT1720 inhibits the reaction [Oxygen results in decreased expression of SOD2 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 mRNA]; sulforaphane inhibits the reaction [Oxygen deficiency results in decreased expression of SOD2 protein]; TNFRSF1A protein affects the reaction [Oxygen results in increased expression of SOD2 mRNA]
3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; [Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein; [Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein; CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Oxygen]; Curcumin inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; DUSP1 mutant form inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; EPAS1 protein affects the reaction [Oxygen deficiency results in increased expression of SOD2 mRNA]; Genistein inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; icariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]; Niacinamide promotes the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]; Plant Extracts inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; Resveratrol inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein]; Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of SOD2 protein]; salvin inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein]; SIRT1 mutant form promotes the reaction [[Oxygen co-treated with Oxygen deficiency] results in decreased expression of SOD2 protein]; SIRT1 mutant form promotes the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of SOD2 protein]; SOD2 protein promotes the reaction [Oxygen deficiency inhibits the reaction [TNF protein results in increased expression of IL1A protein]]; SOD2 protein promotes the reaction [Oxygen deficiency results in decreased expression of IL1A protein]; TXN protein promotes the reaction [Oxygen results in increased activity of SOD2 protein]