GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc8a1 | decreases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in decreased expression of SLC8A1 mRNA | PMID:25937560 | Slc8a1 | increases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in increased expression of SLC8A1 mRNA; Oxygen deficiency results in increased expression of SLC8A1 protein | PMID:17394575 PMID:21293012 | Slc8a1 | multiple interactions | EXP | | 6480464 | CTD | [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of HIF1A protein] which results in increased expression of SLC8A1 mRNA; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SLC8A1 mRNA; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of SLC8A1 protein; HIF1A protein promotes the reaction [Oxygen deficiency results in increased expression of SLC8A1 protein]; Trimetazidine inhibits the reaction [Oxygen deficiency results in decreased expression of SLC8A1 mRNA] | PMID:21293012 PMID:25937560 | |
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