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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2797 Species: Rattus norvegicus RGD Object: Gene Symbol: Hk2 Name: hexokinase 2

Acc ID: CHEBI:15379 Term: dioxygen Definition: An elemental molecule that has formula O2. CasRN: 7782-44-7 Chemical ID: MESH:D010100

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	ISO	RGD:733090	6480464	CTD	Oxygen deficiency results in increased expression of HK2 mRNA	PMID:19502547
increases expression	ISO	RGD:733090	6480464	CTD	Oxygen deficiency results in increased expression of HK2 mRNA	PMID:20042640 PMID:19502547
increases expression	ISO	RGD:733090	6480464	CTD	Oxygen deficiency results in increased expression of HK2 mRNA	PMID:19502547 PMID:20042640
affects expression	ISO	RGD:735576	6480464	CTD	Oxygen deficiency affects the expression of HK2 mRNA	PMID:17193925