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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2661
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gapdh
Name: glyceraldehyde-3-phosphate dehydrogenase
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gapdhincreases expressionEXP 6480464CTDOxygen results in increased expression of GAPDH mRNAPMID:22911455
Gapdhincreases expressionISOGapdh (Mus musculus)6480464CTDOxygen deficiency results in increased expression of GAPDH mRNAPMID:10646848
Gapdhincreases expressionISOGAPDH (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of GAPDH mRNAPMID:10646848 PMID:19502547 PMID:29690507
Gapdhmultiple interactionsISOGapdh (Mus musculus)6480464CTDHIF1A protein affects the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]PMID:10646848
Gapdhmultiple interactionsISOGAPDH (Homo sapiens)6480464CTD[eprenetapopt co-treated with Cisplatin] inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]; Cisplatin inhibits the reaction [Oxygen deficiency results in increased expression of GAPDH mRNA]; Oxygen deficiency promotes the reaction [HIF1A protein binds to GAPDH promoter]PMID:23880069 PMID:29690507
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