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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2375
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Col2a1
Name: collagen type II alpha 1 chain
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Col2a1increases expressionISOCOL2A1 (Homo sapiens)6480464CTDOxygen deficiency results in increased expression of COL2A1 proteinPMID:23406266
Col2a1multiple interactionsISOCOL2A1 (Homo sapiens)6480464CTDcobaltiprotoporphyrin promotes the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of COL2A1 protein]]; HMOX1 mutant form inhibits the reaction [cobaltiprotoporphyrin promotes the reaction [IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of COL2A1 protein]]]; IL1B protein inhibits the reaction [Oxygen deficiency results in increased expression of COL2A1 protein]PMID:23406266
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