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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2070
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Agtr1a
Name: angiotensin II receptor, type 1a
Acc ID: CHEBI:15379
Term: dioxygen
Definition: An elemental molecule that has formula O2.
Chemical ID: MESH:D010100
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Agtr1adecreases expressionEXP 6480464CTDOxygen deficiency results in decreased expression of AGTR1A mRNA; Oxygen deficiency results in decreased expression of AGTR1A proteinPMID:19118600
Agtr1aaffects expressionISOAgtr1a (Mus musculus)6480464CTDOxygen deficiency affects the expression of AGTR1 proteinPMID:25511041
Agtr1adecreases expressionISOAgtr1a (Mus musculus)6480464CTDOxygen deficiency results in decreased expression of AGTR1 proteinPMID:21825224
Agtr1amultiple interactionsISOAgtr1a (Mus musculus)6480464CTDLosartan inhibits the reaction [Oxygen deficiency results in increased expression of AGTR1 protein]PMID:25511041
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