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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112 Species: Rattus norvegicus RGD Object: Gene Symbol: Abcc1 Name: ATP-binding cassette, subfamily C (CFTR/MRP), member 1

Acc ID: CHEBI:15373 Term: biopterin Definition: A pterin derivative that consists of pterin bearing amino, oxo and 1,2-dihydroxypropyl substituents at positions 2, 4 and 6 respectively. The parent of the class of biopterins. CasRN: 22150-76-1 Chemical ID: MESH:D001708

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
affects abundance	ISO	RGD:10919	6480464	CTD	ABCC1 protein affects the abundance of Biopterin analog	PMID:17272743
multiple interactions	ISO	RGD:10919	6480464	CTD	ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Biopterin analog]	PMID:17272743