GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nos3 | increases activity | ISO | NOS3 (Homo sapiens) | 6480464 | CTD | sapropterin results in increased activity of NOS3 protein | PMID:23753407 | Nos3 | multiple interactions | ISO | Nos3 (Mus musculus) | 6480464 | CTD | [NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides; EPO protein inhibits the reaction [[NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides] | PMID:25490417 | Nos3 | multiple interactions | ISO | NOS3 (Homo sapiens) | 6480464 | CTD | sapropterin deficiency inhibits the reaction [NOS3 protein results in increased abundance of Superoxides]; sapropterin deficiency promotes the reaction [NOS3 protein results in increased abundance of Superoxides] | PMID:19011239 | | ||||||||||||||||||||||
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