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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2130
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Apoa1
Name: apolipoprotein A1
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Apoa1affects metabolic processingISOAPOA1 (Homo sapiens)6480464CTDAcrolein affects the metabolism of APOA1 proteinPMID:16037261 PMID:16126721
Apoa1multiple interactionsISOAPOA1 (Homo sapiens)6480464CTD[Acrolein affects the metabolism of APOA1 protein] which results in decreased secretion of Cholesterol; Acrolein inhibits the reaction [APOA1 protein affects the transport of Cholesterol]PMID:16037261 PMID:16126721
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