• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736042 Species: Homo sapiens RGD Object: Gene Symbol: IGFBP3 Name: insulin-like growth factor binding protein 3

Acc ID: CHEBI:15367 Term: all-trans-retinoic acid Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. CasRN: 302-79-4 Chemical ID: MESH:D014212

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:16012519 PMID:15982314 PMID:16480812 PMID:16951191
increases expression	ISO	RGD:10774	6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:16604517
multiple interactions	ISO	RGD:2874	6480464	CTD	Tretinoin affects the reaction [Oxygen affects the secretion of IGFBP3 protein]	PMID:16055936
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:16480812 PMID:21934132 PMID:16951191 PMID:16012519 PMID:15982314
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:16480812 PMID:16951191 PMID:15982314 PMID:21934132 PMID:16012519
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:21934132 PMID:16951191 PMID:16480812 PMID:15982314 PMID:16012519
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:16480812 PMID:15982314 PMID:21934132 PMID:16012519 PMID:16951191
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:15982314 PMID:21934132 PMID:16480812 PMID:16951191 PMID:16012519
increases expression	EXP		6480464	CTD	Tretinoin results in increased expression of IGFBP3 mRNA	PMID:15982314 PMID:16012519 PMID:16480812 PMID:16951191 PMID:21934132