GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | Tretinoin affects the localization of RELA protein | PMID:18280257 | Rela | decreases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of RELA mRNA; Tretinoin results in decreased expression of RELA protein | PMID:15498508 PMID:17701358 PMID:18098270 PMID:18922099 PMID:30093655 | Rela | increases expression | ISO | RELA (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of RELA mRNA | PMID:16054129 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | [SN50 peptide affects the localization of [RELA protein binds to NFKB1 protein]] inhibits the reaction [Tretinoin results in increased expression of GRIN1 protein]; [SN50 peptide affects the localization of [RELA protein binds to NFKB1 protein]] inhibits the reaction [Tretinoin results in increased expression of SOD2 protein]; [Tretinoin co-treated with Paclitaxel] results in decreased expression of RELA protein; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of RELA protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of RELA protein] | PMID:17701358 PMID:18098270 PMID:18280257 PMID:30093655 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | Tretinoin affects the reaction [RELA protein binds to SLC11A2 promoter]; Tretinoin inhibits the reaction [Carbon Tetrachloride results in increased activity of RELA protein] | PMID:16232120 PMID:18397230 | | ||||||||||||||||||||||
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