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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1increases expressionEXP 6480464CTDTretinoin results in increased expression of CDH1 mRNAPMID:24977338
Cdh1affects expressionISOCDH1 (Homo sapiens)6480464CTDTretinoin affects the expression of CDH1 mRNAPMID:17034753 PMID:31600526
Cdh1affects expressionISOCdh1 (Mus musculus)6480464CTDTretinoin affects the expression of CDH1 mRNAPMID:16211290
Cdh1decreases expressionISOCDH1 (Homo sapiens)6480464CTDTretinoin results in decreased expression of CDH1 mRNAPMID:23724009
Cdh1increases expressionISOCDH1 (Homo sapiens)6480464CTDTretinoin results in increased expression of CDH1 mRNA; Tretinoin results in increased expression of CDH1 proteinPMID:21934132 PMID:23527294 PMID:30093655
Cdh1increases expressionISOCdh1 (Mus musculus)6480464CTDTretinoin results in increased expression of CDH1 mRNAPMID:16236135 PMID:16788091
Cdh1multiple interactionsISOCDH1 (Homo sapiens)6480464CTDArsenic Trioxide promotes the reaction [Tretinoin results in increased expression of CDH1 mRNA]; Tretinoin promotes the reaction [Arsenic Trioxide results in increased expression of CDH1 mRNA]PMID:30093655
Cdh1multiple interactionsISOCdh1 (Mus musculus)6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of CDH1 mRNA; [bisphenol S co-treated with Tretinoin] results in decreased expression of CDH1 mRNA; [perfluorooctane sulfonic acid co-treated with Tretinoin] results in decreased expression of CDH1 mRNA; [perfluorooctanoic acid co-treated with Tretinoin] results in decreased expression of CDH1 mRNAPMID:23948355 PMID:30951980
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