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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628742
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lgi1
Name: leucine-rich, glioma inactivated 1
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lgi1decreases expressionEXP 6480464CTDTretinoin results in decreased expression of LGI1 mRNAPMID:20488242
Lgi1decreases expressionISOLGI1 (Homo sapiens)6480464CTDTretinoin results in decreased expression of LGI1 mRNAPMID:21934132
Lgi1increases expressionISOLGI1 (Homo sapiens)6480464CTDTretinoin results in increased expression of LGI1 mRNAPMID:23724009
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