GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mcl1 | decreases expression | ISO | MCL1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of MCL1 mRNA | PMID:17034753 | Mcl1 | increases expression | ISO | MCL1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of MCL1 mRNA; Tretinoin results in increased expression of MCL1 protein | PMID:16572199 PMID:19176369 PMID:33167477 | Mcl1 | increases expression | ISO | Mcl1 (Mus musculus) | 6480464 | CTD | Tretinoin results in increased expression of MCL1 mRNA | PMID:16604517 | Mcl1 | multiple interactions | ISO | MCL1 (Homo sapiens) | 6480464 | CTD | [Tretinoin co-treated with TGFB1 protein] results in increased expression of MCL1 protein; [Tretinoin co-treated with zoledronic acid] results in decreased expression of MCL1 mRNA; PI103 inhibits the reaction [Tretinoin results in increased expression of MCL1 protein] | PMID:16242776 PMID:19176369 PMID:20349282 | | ||||||||||||||||||||||
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